The Journal of Clinical Oncology

 Leiomyosarcoma Of The Scalp.

Correspondence to Author: Nunzio Di Naro1, Marta Meloni1, Francesca Ledda1, Chiara Floris1, Giovanni Antonio Tolu1,2., 

1. Operational Unit of Pathologic Anatomy, Hospital “San Martino”, Oristano, Italy.
2. Director of the Operational Unit of Pathologic Anatomy, “San Martino” Hospital, Oristano, Italy

Abstract:

We describe a case of an elderly male subject with a primary diagnosis of leiomyosarcoma of the scalp, whose peculiarity lies in both the rarity of this tumor and its unusual site.

Keywords :
leiomyosarcoma, scalp, soft tissue tumors.

Introduction: Soft tissue sarcomas are a very rare disease, comprising about 1% of malignancies. These are rare, aggressive mesenchymal neoplasms that originate from smooth muscle. The most frequent sites of occurrence are the gastrointestinal tract, retroperitoneum, and in women the uterine site is common. Superficial leiomyosarcomas in particular account for 7-10% of total leiomyosarcoma cases, and the most frequent sites are the extremities, especially the lower extremities, followed by the head and neck region. The etiology is unknown; some correlations with radiation and chemical exposure, trauma, and genetic mutations have been established [1,2] and they have been associated with bilateral hereditary retinoblastoma ( the result of mutations or deletions on the RB 1 gene) [3].

Citation:

Meloni Marta. Leiomyosarcoma Of The Scalp. The Journal of Clinical Oncology 2025.

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